Lipid Metabolism Profiles in Rheumatic Diseases

Fasting and rheumatic diseases

Fasting is one of the important religious practices of Muslims, in which the individuals abstain from eating and drinking from dawn to sunset. Fasting is not obligatory or even not allowed, in case it causes health problems to the fasting individual. Rheumatic diseases are a major group of chronic diseases which can bring about numerous problems while fasting. The aim of this article is to revi...

Metabolism of Hyaluronic Acid in Relation to Rheumatic Diseases.

The diffidence with which I approach the subject of hyaluronic acid and rheumatism is born of a conjugation of both personal and general ignorance. Our knowledge of the functional and intrinsic pathology of that group of locomotor disorders which we label " the rheumatic diseases " is so meagre that any new facts, however tenuous their nexus with rheumatism may appear to be, are seized on avidl...

Energy metabolism and rheumatic diseases: from cell to organism

In rheumatic and other chronic inflammatory diseases, high amounts of energy for the activated immune system have to be provided and allocated by energy metabolism. In recent time many new insights have been gained into the control of the immune response through metabolic signals. Activation of immune cells as well as reduced nutrient supply and hypoxia in inflamed tissues cause stimulation of ...

Adipokines and Systemic Rheumatic Diseases: Linking Inflammation, Immunity and Metabolism

Epigenetics in rheumatic diseases

With enormous speed novel data are emerging about regulating the expression of the genetically encoded information [1]. This highly complex regulatory network called epigenetics includes acetylation, methylation, phosphorylation, sumoylation and non-coding RNAs (ncRNA), such as miRNA and lncRNAs. Our laboratory is addressing over the past decade inflammatory rheumatic diseases [2], like rheumat...